Oral favipiravir for patients with delayed SARS-CoV-2 viral RNA clearance: a case series.
Identifieur interne : 000388 ( Main/Exploration ); précédent : 000387; suivant : 000389Oral favipiravir for patients with delayed SARS-CoV-2 viral RNA clearance: a case series.
Auteurs : Dian Fu [République populaire de Chine] ; Ruiyuan Cao [République populaire de Chine] ; Lei Zhao [République populaire de Chine] ; Wei Li [République populaire de Chine] ; Wu Zhong [République populaire de Chine] ; Jiqiu Wen [République populaire de Chine]Source :
- Critical care (London, England) [ 1466-609X ] ; 2020.
Descripteurs français
- KwdFr :
- ARN viral (analyse), Administration par voie orale (MeSH), Adulte d'âge moyen (MeSH), Amides (administration et posologie), Amides (usage thérapeutique), Antiviraux (administration et posologie), Antiviraux (usage thérapeutique), Betacoronavirus (MeSH), Excrétion virale (effets des médicaments et des substances chimiques), Femelle (MeSH), Humains (MeSH), Infections à coronavirus (traitement médicamenteux), Mâle (MeSH), Pandémies (MeSH), Pneumopathie virale (traitement médicamenteux), Pyrazines (administration et posologie), Pyrazines (usage thérapeutique), Sujet âgé (MeSH).
- MESH :
- administration et posologie : Amides, Antiviraux, Pyrazines.
- analyse : ARN viral.
- effets des médicaments et des substances chimiques : Excrétion virale.
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- usage thérapeutique : Amides, Antiviraux, Pyrazines.
- Administration par voie orale, Adulte d'âge moyen, Betacoronavirus, Femelle, Humains, Mâle, Pandémies, Sujet âgé.
English descriptors
- KwdEn :
- Administration, Oral (MeSH), Aged (MeSH), Amides (administration & dosage), Amides (therapeutic use), Antiviral Agents (administration & dosage), Antiviral Agents (therapeutic use), Betacoronavirus (MeSH), Coronavirus Infections (drug therapy), Female (MeSH), Humans (MeSH), Male (MeSH), Middle Aged (MeSH), Pandemics (MeSH), Pneumonia, Viral (drug therapy), Pyrazines (administration & dosage), Pyrazines (therapeutic use), RNA, Viral (analysis), Virus Shedding (drug effects).
- MESH :
- chemical , administration & dosage : Amides, Antiviral Agents, Pyrazines.
- chemical , analysis : RNA, Viral.
- chemical , therapeutic use : Amides, Antiviral Agents, Pyrazines.
- drug effects : Virus Shedding.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- Administration, Oral, Aged, Betacoronavirus, Female, Humans, Male, Middle Aged, Pandemics.
DOI: 10.1186/s13054-020-03288-5
PubMed: 32977854
PubMed Central: PMC7517732
Affiliations:
Links toward previous steps (curation, corpus...)
Le document en format XML
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China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850</wicri:regionArea><wicri:noRegion>100850</wicri:noRegion></affiliation></author><author><name sortKey="Li, Wei" sort="Li, Wei" uniqKey="Li W" first="Wei" last="Li">Wei Li</name><affiliation wicri:level="1"><nlm:affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850</wicri:regionArea><wicri:noRegion>100850</wicri:noRegion></affiliation></author><author><name sortKey="Zhong, Wu" sort="Zhong, Wu" uniqKey="Zhong W" first="Wu" last="Zhong">Wu 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de Chine</country><wicri:regionArea>Wuhan Huoshenshan Hospital, Wuhan, 430100</wicri:regionArea><wicri:noRegion>430100</wicri:noRegion></affiliation></author><author><name sortKey="Cao, Ruiyuan" sort="Cao, Ruiyuan" uniqKey="Cao R" first="Ruiyuan" last="Cao">Ruiyuan Cao</name><affiliation wicri:level="1"><nlm:affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850</wicri:regionArea><wicri:noRegion>100850</wicri:noRegion></affiliation></author><author><name sortKey="Zhao, Lei" sort="Zhao, Lei" uniqKey="Zhao L" first="Lei" last="Zhao">Lei Zhao</name><affiliation wicri:level="1"><nlm:affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850</wicri:regionArea><wicri:noRegion>100850</wicri:noRegion></affiliation></author><author><name sortKey="Li, Wei" sort="Li, Wei" uniqKey="Li W" first="Wei" last="Li">Wei Li</name><affiliation wicri:level="1"><nlm:affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850</wicri:regionArea><wicri:noRegion>100850</wicri:noRegion></affiliation></author><author><name sortKey="Zhong, Wu" sort="Zhong, Wu" uniqKey="Zhong W" first="Wu" last="Zhong">Wu Zhong</name><affiliation wicri:level="1"><nlm:affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China. zhongwu@bmi.ac.cn.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850</wicri:regionArea><wicri:noRegion>100850</wicri:noRegion></affiliation></author><author><name sortKey="Wen, Jiqiu" sort="Wen, Jiqiu" uniqKey="Wen J" first="Jiqiu" last="Wen">Jiqiu Wen</name><affiliation wicri:level="1"><nlm:affiliation>National Clinical and Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002, China. wjqkidney@hotmail.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>National Clinical and Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002</wicri:regionArea><wicri:noRegion>210002</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:affiliation>Wuhan Huoshenshan Hospital, Wuhan, 430100, China. wjqkidney@hotmail.com.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Wuhan Huoshenshan Hospital, Wuhan, 430100</wicri:regionArea><wicri:noRegion>430100</wicri:noRegion></affiliation></author></analytic><series><title level="j">Critical care (London, England)</title><idno type="eISSN">1466-609X</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Oral (MeSH)</term><term>Aged (MeSH)</term><term>Amides (administration & dosage)</term><term>Amides (therapeutic use)</term><term>Antiviral Agents (administration & dosage)</term><term>Antiviral Agents (therapeutic use)</term><term>Betacoronavirus (MeSH)</term><term>Coronavirus Infections (drug therapy)</term><term>Female (MeSH)</term><term>Humans (MeSH)</term><term>Male (MeSH)</term><term>Middle Aged (MeSH)</term><term>Pandemics (MeSH)</term><term>Pneumonia, Viral (drug therapy)</term><term>Pyrazines (administration & dosage)</term><term>Pyrazines (therapeutic use)</term><term>RNA, Viral (analysis)</term><term>Virus Shedding (drug effects)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>ARN viral (analyse)</term><term>Administration par voie orale (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Amides (administration et posologie)</term><term>Amides (usage thérapeutique)</term><term>Antiviraux (administration et posologie)</term><term>Antiviraux (usage thérapeutique)</term><term>Betacoronavirus (MeSH)</term><term>Excrétion virale (effets des médicaments et des substances chimiques)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Mâle (MeSH)</term><term>Pandémies (MeSH)</term><term>Pneumopathie virale (traitement médicamenteux)</term><term>Pyrazines (administration et posologie)</term><term>Pyrazines (usage thérapeutique)</term><term>Sujet âgé (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Amides</term><term>Antiviral Agents</term><term>Pyrazines</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>RNA, Viral</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Amides</term><term>Antiviral Agents</term><term>Pyrazines</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Amides</term><term>Antiviraux</term><term>Pyrazines</term></keywords><keywords scheme="MESH" qualifier="analyse" xml:lang="fr"><term>ARN viral</term></keywords><keywords scheme="MESH" qualifier="drug effects" xml:lang="en"><term>Virus Shedding</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="effets des médicaments et des substances chimiques" xml:lang="fr"><term>Excrétion virale</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Amides</term><term>Antiviraux</term><term>Pyrazines</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Administration, Oral</term><term>Aged</term><term>Betacoronavirus</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Pandemics</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Administration par voie orale</term><term>Adulte d'âge moyen</term><term>Betacoronavirus</term><term>Femelle</term><term>Humains</term><term>Mâle</term><term>Pandémies</term><term>Sujet âgé</term></keywords></textClass></profileDesc></teiHeader></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">32977854</PMID><DateCompleted><Year>2020</Year><Month>10</Month><Day>08</Day></DateCompleted><DateRevised><Year>2020</Year><Month>10</Month><Day>08</Day></DateRevised><Article PubModel="Electronic"><Journal><ISSN IssnType="Electronic">1466-609X</ISSN><JournalIssue CitedMedium="Internet"><Volume>24</Volume><Issue>1</Issue><PubDate><Year>2020</Year><Month>09</Month><Day>25</Day></PubDate></JournalIssue><Title>Critical care (London, England)</Title><ISOAbbreviation>Crit Care</ISOAbbreviation></Journal><ArticleTitle>Oral favipiravir for patients with delayed SARS-CoV-2 viral RNA clearance: a case series.</ArticleTitle><Pagination><MedlinePgn>578</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1186/s13054-020-03288-5</ELocationID><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Fu</LastName><ForeName>Dian</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>National Clinical and Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002, China.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wuhan Huoshenshan Hospital, Wuhan, 430100, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cao</LastName><ForeName>Ruiyuan</ForeName><Initials>R</Initials><AffiliationInfo><Affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhao</LastName><ForeName>Lei</ForeName><Initials>L</Initials><AffiliationInfo><Affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Li</LastName><ForeName>Wei</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Zhong</LastName><ForeName>Wu</ForeName><Initials>W</Initials><AffiliationInfo><Affiliation>National Engineering Research Center for the Emergency Drug, Beijing Institute of Pharmacology and Toxicology, Beijing, 100850, China. zhongwu@bmi.ac.cn.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wen</LastName><ForeName>Jiqiu</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>National Clinical and Research Center of Kidney Diseases, Jinling Hospital, Nanjing University School of Medicine, Nanjing, 210002, China. wjqkidney@hotmail.com.</Affiliation></AffiliationInfo><AffiliationInfo><Affiliation>Wuhan Huoshenshan Hospital, Wuhan, 430100, China. wjqkidney@hotmail.com.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>2018ZX09711003</GrantID><Agency>National Science and Technology Major Project</Agency><Country>International</Country></Grant><Grant><GrantID>2020YFC0841700</GrantID><Agency>National Key R&D program of China</Agency><Country>International</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2020</Year><Month>09</Month><Day>25</Day></ArticleDate></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Crit Care</MedlineTA><NlmUniqueID>9801902</NlmUniqueID><ISSNLinking>1364-8535</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000577">Amides</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D000998">Antiviral Agents</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D011719">Pyrazines</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012367">RNA, Viral</NameOfSubstance></Chemical><Chemical><RegistryNumber>EW5GL2X7E0</RegistryNumber><NameOfSubstance UI="C462182">favipiravir</NameOfSubstance></Chemical></ChemicalList><SupplMeshList><SupplMeshName Type="Disease" UI="C000657245">COVID-19</SupplMeshName><SupplMeshName Type="Organism" UI="C000656484">severe acute respiratory syndrome coronavirus 2</SupplMeshName></SupplMeshList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000284" MajorTopicYN="N">Administration, Oral</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000577" MajorTopicYN="N">Amides</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000998" MajorTopicYN="N">Antiviral Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000073640" MajorTopicYN="N">Betacoronavirus</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018352" MajorTopicYN="N">Coronavirus Infections</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D058873" MajorTopicYN="N">Pandemics</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000188" MajorTopicYN="Y">drug therapy</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011719" MajorTopicYN="N">Pyrazines</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000627" MajorTopicYN="Y">therapeutic use</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012367" MajorTopicYN="N">RNA, Viral</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017201" MajorTopicYN="N">Virus Shedding</DescriptorName><QualifierName UI="Q000187" MajorTopicYN="Y">drug effects</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="Y">COVID-19</Keyword><Keyword MajorTopicYN="Y">Favipiravir</Keyword><Keyword MajorTopicYN="Y">SARS-CoV-2</Keyword><Keyword MajorTopicYN="Y">viral RNA persistence</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2020</Year><Month>07</Month><Day>27</Day></PubMedPubDate><PubMedPubDate 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18;:</Citation><ArticleIdList><ArticleId IdType="pubmed">32346491</ArticleId></ArticleIdList></Reference><Reference><Citation>Int J Infect Dis. 2020 Jun;95:433-435</Citation><ArticleIdList><ArticleId IdType="pubmed">32353545</ArticleId></ArticleIdList></Reference></ReferenceList></PubmedData></pubmed><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Fu, Dian" sort="Fu, Dian" uniqKey="Fu D" first="Dian" last="Fu">Dian Fu</name></noRegion><name sortKey="Cao, Ruiyuan" sort="Cao, Ruiyuan" uniqKey="Cao R" first="Ruiyuan" last="Cao">Ruiyuan Cao</name><name sortKey="Fu, Dian" sort="Fu, Dian" uniqKey="Fu D" first="Dian" last="Fu">Dian Fu</name><name sortKey="Li, Wei" sort="Li, Wei" uniqKey="Li W" first="Wei" last="Li">Wei Li</name><name sortKey="Wen, Jiqiu" sort="Wen, Jiqiu" uniqKey="Wen J" first="Jiqiu" last="Wen">Jiqiu Wen</name><name sortKey="Wen, Jiqiu" sort="Wen, Jiqiu" uniqKey="Wen J" first="Jiqiu" last="Wen">Jiqiu Wen</name><name sortKey="Zhao, Lei" sort="Zhao, Lei" uniqKey="Zhao L" first="Lei" last="Zhao">Lei Zhao</name><name sortKey="Zhong, Wu" sort="Zhong, Wu" uniqKey="Zhong W" first="Wu" last="Zhong">Wu Zhong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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